翻訳と辞書 Words near each other ・ Terminalia richii ・ Terminalia schimperiana ・ Terminalia sericea ・ Terminalia superba ・ Terminaline ・ TerminaLink ・ Terminalis ・ Terminally redundant DNA ・ Terminate ・ Terminate (software) ・ Terminate and stay resident program ・ Terminate Damnation ・ Terminate with extreme prejudice ・ Terminated Merchant File ・ Terminating deposit ・ Terminal deoxynucleotidyl transferase ・ Terminal Dirge ・ Terminal Doppler Weather Radar ・ Terminal drop hypothesis ・ Terminal dwell time ・ Terminal Earth ・ Terminal elevator ・ Terminal emulator ・ Terminal Entry ・ Terminal equipment ・ Terminal Error ・ Terminal Exposure ・ Terminal Freeze ・ Terminal Frost ・ Terminal guidance Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Terminal deoxynucleotidyl transferase ： ウィキペディア英語版 Terminal deoxynucleotidyl transferase Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells. TdT adds N-nucleotides to the V,D, and J exons during antibody gene recombination, enabling the phenomenon of junctional diversity. In humans, terminal transferase is encoded by the ''DNTT'' gene. TdT is absent in fetal liver HSCs, significantly impairing junctional diversity in B-cells during the fetal period. ==Function== TdT catalyses the addition of nucleotides to the 3' terminus of a DNA molecule. Unlike most DNA polymerases, it does not require a template. The preferred substrate of this enzyme is a 3'-overhang, but it can also add nucleotides to blunt or recessed 3' ends. Cobalt is a necessary cofactor, however the enzyme catalyzes reaction upon Mg and Mn administration ''in vitro''. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Terminal deoxynucleotidyl transferase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.